Milestone in Cancer Stem Cell Research

Pao Pereira Fights Cancer Stem Cells!

New research just published in Integrative Cancer Therapies shows that the Pao pereira plant extract inhibits pancreatic cancer stem cells. This dramatic result means that the extract will be useful for preventing cancer recurrence.

Everyone knows that cancer treatments are not cancer cures. Chemotherapy treatments kill cancer cells and shrink tumors, but the cancer often comes back. Cancer stem cells (CSCs) are the culprit because they are resistant to anti-cancer drugs, they can metastasize and form new tumors. CSCs make up a small fraction of the cells in a tumor that survive after the majority of primary cancer cells are killed by anti-cancer drugs. The CSCs persist, spread and restart tumor growth.

CSCs are also referred to as cancer stem-like cells because they share the capacity for self-proliferation with normal stem cells that are involved in the renewal and repair of tissues, but unlike normal stem cells, CSCs are cancerous and drug resistant.

In vitro experiments show Pao pereira reducing the number of pancreatic CSCs (see figure below).

As the amount of Pao pereira is increased, the number of pancreatic cancer stem cells (spheroids) decrease dramatically. In additional cell-based studies, the Pao pereira extract also specifically reduced the pancreatic cancer stem cell population.

In vivo experiments showed that Pao pereira inhibited the capacity of pancreatic CSCs to form tumors – the defining characteristic of CSCs – and significantly reduce the volume of tumors that did form (see figure below).

At day 6 (Figure A), tumor formation rate in the control group reached 80%, while in Pao-treated group it was only 10%. At day 20, when the treatment stopped, all mice in control group were bearing tumors on both flanks (100% tumor formation), while the Pao-treated group only had 30% tumor formation. Growth of the formed tumors was also inhibited by Pao pereira treatment compared with the control group (Figure B). A long-term inhibitory effect in tumor growth was observed after treatment had stopped. Pao pereira works by lowering the signals that trigger the pancreatic cancer stem-like cell properties that lead to cancer recurrence.

The researchers at Kansas University Medical Center concluded that Pao pereira holds great promise as a novel treatment for targeting pancreatic CSCs, an essential component of treatments that will lead to real cancer cures.

Extract of the Medicinal Plant Pao Pereira Inhibits Pancreatic Cancer Stem-Like Cell In Vitro and In Vivo
Dong, P. Chen and Q Chen. Integrative Cancer Therapies. July 2018. doi: 10.1177/1534735418786027

Maison Beljanski presents Healthy Tuesdays: Inflammation

August 28th was the second in a new series of events called Healthy Tuesdays, which are a unique networking and educational opportunity for guests to experience stimulating, non-conventional, thought-provoking health talks by doctors and specialists.

Inflammation is extremely common and suffered by too many people.  Below are a few facts on the topic:

What is Inflammation?

—> The Body’s Response to Injury

Top 10 Causes

1. Foods with a High Glycemic Index
2. Trans Fats
3. Saturated Animal Fats 
4. Excessive Alcohol Consumption
5. Celiac Disease
6. Smoking
7. Chronic Stress
8. Obesity
9. High ratio Omega-6 to Omega-3 Polyunsaturated fatty acids
10. Pollution and Environmental Toxins

Top 10 Foods to Avoid

1. Sugar
2. Vegetable Oil
3. Fried Food 
4. Refined Flour
5. Dairy
6. Artificial Sweetener
7. Artificial Additives
8. Saturated Fats
9. Conventional Grain-Fed Meats
10. Processed Meats

Top 10 Foods to Reduce Inflammation

1. Healthy Oils
2. Fish
3. Nuts
4. Fruit  
5. Garlic
6. Herbs
7. Chocolate
8. Tea
9. Beans
10. Onions

Now that the basics have been established, Healthy Tuesdays presented Three Ways to Address Inflammation with Three powerful keynote speakers:

Dr. Richard Carlton – Physician specializing in Integrative Psychiatry who has been a pioneer in the rational use of nutrition-based treatment approaches. His presentation focused on the positive interaction of medical cannabis to treat inflammation in one’s body.
Dr. John Hall – Director of Research for The Beljanski Foundation. He educated the group about the anti-inflammatory effect and multi-organ benefits of Pao pereira which has been proven on studies within the prostate and pancreas.
Dr. Larisa Likver – Board-certified physiatrist with over 20 years of medical experience, specifically pain management, both in New York City and internationally. She provided the group with an understanding of how to repair painful musculoskeletal damage at the root.

The event was full of energy and each speaker was highly fascinating. We are greatly anticipating the next event on October 2nd featuring Men’sHealth. Register here!

Mirko Beljanski: A new article in The Optimist Daily!

optimist

by Sylvie Beljanski

We are pleased to share with you a long article written by Janet Rae-Dupree, entitled “Can a plant heal cancer patients?”, and recently published online in  The Optimist Daily1.

The article recounts the amazing story of my father Mirko Beljanski, Father of environmental medicine, and his groundbreaking scientific discoveries. You will learn “how Mirko Beljanski’s lifelong research path come to open new avenues for treating cancer and, possibly, preventing its development in the first place”.

Here is an excerpt of  this well-documented article:

“[…] Beljanski is one of the first molecular biologists to study RNA and its role in cell regulation. His work ultimately upended the previous accepted wisdom about what makes cancerous cells different from normal cells and brings us to today’s ongoing research at centers in the United States, where the plant extracts he refined are making advances against prostate, pancreatic, ovarian and even brain cancer and the RNA fragments […].

Beljanski’s career began at the same time that the field of molecular biology did, with the discovery of how DNA’s double helix stores and deploys genetic information. For more than 40 years, molecular biologists focused solely on genetics, protein expression and how mutations to genes could cause cancer. Study the “letters” of the genetic alphabet, the theory went, and you would spot “typos” that lead to cancer. Figure out how to prevent those typos and you could learn how to stop cancer in its tracks.

But Beljanski demonstrated that the primary physical difference between normal and cancerous DNA lies within the structure of the double helix itself. DNA in cancerous cells has unwound, leaving gaping loops and holes where the two curving sides of the double helix fail to latch securely to each other any longer.[…]”.

Click here to read the entire article, and feel free to share it with your friends and family. Information is the first step to taking care of your health after all!


REFERENCES

1- “Can a plant heal cancer patients?The Optimist Daily published online in May 2017

APRIL 27-29, 2017: International Integrative Oncology Conference – San Diego, CA

bacf-logo-awf-2012Come visit us at the International Integrative Oncology Conference, booth #6, to learn more about the important work of the Beljanski Foundation in searching for natural cures for cancer and other chronic diseases including the latest information regarding the scientific research underway on the effects of Dr. Mirko Beljanski’s plant extracts on cancer stem cells.

Don’t miss the presentation “Immune Support for Chemotherapy Patients” by Dr. John Hall, Senior Scientific Advisor of the Beljanski Foundation, on Friday, April 28th at 11:00 am.

Date:
April 27-29, 2017

Location:
Town and Country Resort and Convention Center
500 Hotel Circle North
San Diego, CA 92108

Learn More:
Best Answer For Cancer 2017 Conference

CAM

MARCH 2-4, 2017: Complementary & Alternative Cancer Therapies Conference – West Palm Beach, FL

annie apple seedDo not miss the opportunity to meet us at the 11th Annual Complementary & Alternative Cancer Therapies Conference in West Palm Beach.  Stop by our booth to learn more about the work of the Beljanski Foundation, and do not miss the presentation “Plant Extracts for Ovarian and Pancreatic Cancers and Cancer Stem Cells” by the Vice President of the Beljanski Foundation, Sylvie Beljanski on Friday, March 3rd, at 8:55 AM.

Date:
March 2-4, 2017

Location:Embassy Suites Hotel
1601 Belvedere Rd
West Palm Beach, FL 33406

Learn More:
11th Annual Complementary & Alternative Cancer Therapies Conference

Interview in the “Late Night Health” with Mark Alyn

markalyn_latenight_banner-1On August 29th, Sylvie Beljanski joined Late Night Health for a lively discussion on plant-based foods and Environmental medicine with Mark Alyn.

Late Night Health is a radio show dedicated to provide people with healthcare information covering a wide range of topics such as traditional, complementary, and alternative health issues that people can relate to.

Sylvie Beljanski introduced The Beljanski Foundation and discussed about the legacy of Mirko Beljanski. His early findings at the Pasteur Institute in France focused on the healing power of botanical extracts. Hence, the Beljanski Foundation, in partnership with prestigious American institutions, such as the Columbia University Medical Center and the University of Kansas Medical Center, bases their research on natural compounds with anti-cancer properties (Pao pereira and Rauwolfia vomitoria). The recent research in Environmental Medicine have shown promising results regarding patients diagnosed with cancer.

The promising results represent a significant breakthrough for the Environmental Medicine.

You can listen to the interview (two parts): Part 1   Part 2

Interview in “Hutch in the Morning” on WBTM

Sylvie Beljanski©The Beljanski Foundation, Inc.Sylvie Beljanski was interviewed by Dave “Hutch” Hutcheson on WBTM, in Hutch in the morning to talk about The Beljanski Foundation. Sylvie Beljanski introduced the Foundation and the studies they are conducting based on the research of Mirko Beljanski, considered as the father of Environmental Medicine. The Beljanski Foundation carries on the legacy of Mirko Beljanski by continuing the research against cancer.

You can listen to the interview here.

Interview in “Steve Fast’s Show” on WJBC

1400_wjbcamOn August 28th, Sylvie Beljanski, Vice-President of The Beljanski Foundation, was Steve Fast’s guest on WJBC. Sylvie Beljanski presented Mirko Beljanski’s research on natural compounds with anti-cancer properties such as Pao pereira or Rauwolfia vomitoria extract. She also presented the published research conducted on those compounds by prestigious American institutions, such as Columbia University Medical Center and the Cancer Treatment Centers of America and funded by The Beljanski Foundation.

The efficacy and lack of toxicity of the Pao pereira extract (as prepared by Dr. Beljanski) on different types of cancer cells and on synergy with chemotherapy has been confirmed by the recent studies.

You can listen to the interview here.

New article in the Townsend Letter: A Natural Approach to Cancer

The Natural Approach to Cancer

READ THE FULL ARTICLE

beljanskicoverweb1-copyThe Magazine Townsend Letter has published an article written by Sylvie Beljanski, the Vice-President of the Beljanski Foundation and daughter of Mirko Beljanski, Issue of August – September 2016. In the article titled “The Natural Approach to Cancer” Sylvie Beljanski explains that her father’s research has proved the correlation between the environment and its effects on the DNA. The environment, especially the one we are living in, with all the pollution and toxins for instance, constitutes one of the major causes of cancer. Mirko Beljanski is now considered as the father of Environmental Medicine for all the knowledge and progress his research brought to the war on cancer.

His dedication to find a cure to cancer of any kind with natural resources led him to discover natural extracts such as the Pao pereira, the Rauwolfia vomitoria, or the golden leaf of Ginkgo which help to re-organize a destabilized DNA.

Carrying on the legacy of Mirko Beljanski, and over the last 17 years The Beljanski Foundation has developed a research program with several high profile institutions to rigorously assess the anti-cancer potential of identified natural compounds.

All of those publications were published on peer reviewed Medical Journal and are available on Pubmed.gov (the US National Library of Medicine National Institutes of Health).

Prostate cancer

Columbia UniversityPre-cancerous and cancerous cells at Columbia University Medical Center

At Columbia University’s Department of Holistic Urology, preclinical and clinical studies were conducted with two plant extracts, Pao pereira and Rauwolfia vomitoria on prostate cancer cells and on men with prostate issues.

Advanced Cancer cells resistant to hormonal treatment at Nanjing University

Nanjing_UniversityThe research team at Nanjing University used innovative techniques to demonstrate that the Pao pereira extract is effective even against prostate cancer cells that no longer responded to androgen deprivation therapy.

Pancreatic Cancer at Kansas University Medical Center

Kansas university

Research was recently completed at Kansas University Medical Center where the effects of Pao pereira and Rauwolfia vomitoria were analyzed on pancreatic cancer cells. Two new scientific articles were published confirming the excellent results of these studies and the synergy with conventional chemotherapies. Over the course of the study, the Pao pereira was seen to suppress tumor growth significantly, by up to 72% and Gemcitabine at the dose used did not provide any reduction in tumor weight, when Rauwolfia vomitoria alone decreased tumor weight by 53% at the daily dose of 20 mg/kg, and 46% at the daily dose of 50 mg/kg, compared with saline-treated control. By combining Rauwolfia vomitoria with Gemcitabine, the decrease in tumor weight was 56% at both Rauwolfia vomitoria doses.

Ovarian Cancer at Kansas University Medical Center

The scientific team found that Rauwolfia vomitoria was effective against ovarian cancer cells both alone and in combination with carboplatin. The combination decreased tumor size in animal experiments by 87 to 90% and a second study concludes that “In vivo, Pao pereira alone suppressed tumor growth by 79% and decreased volume of ascites by 55%. When Pao pereira was combined with carboplatin, tumor inhibition reached 97% and ascites was completely eradicated.

Clinical Trial on Thrombocytopenia at Cancer Treatment Center of America

Cancer Treatment Center of AmericaSmall RNA fragments that specifically trigger DNA synthesis in healthy bone marrow stem cells, were used in another clinical trial for platelet support. The data reveals that E. coli RNA fragments stimulate platelet proliferation in chemotherapy patients. The study also proved that the source from which the RNA fragments are prepared is critical. The study concluded that Patients receiving E. coli RNA fragments demonstrated a more rapid recovery in platelet count and higher nadir platelet count. None of the patients receiving the E. coli RNA fragments required a chemotherapy dose reduction due to thrombocytopenia.

For more details, you can read the full article click here: The Natural Approach to Cancer.