Mirko Beljanski (1923-1998) a biochemist and biologist, who spent his professional career at the Pasteur Institute in Paris, studying the causes and mechanisms of gene activation, cell division and tissue development in both normal and malignant states, created a sensitive analysis, the “Oncotest”, which allowed him to identify the carcinogenic potential of different molecules often present in our daily surroundings .(1)
Using his Oncotest, Beljanski focused on a secondary alkaloid present in Rauwolfia vomitoria: alstonine, which has been isolated and studied since 1952.(2) Beljanski perfected a Rauwolfia vomitoria extract standardized in alstonine, but devoid of reserpine. Beljanski noted that once reserpine was removed from the Rauwolfia vomitoria extract, the extract had very low toxicity, no hypertensive effect, but a selective effect on cancer cells.(3) Alstonine is so specific to cancerous cells that Beljanski used it as a diagnostic agent designed for selective detection of tumors in cytogenetic tests. The diagnostic agent has application in preoperative and postoperative diagnoses. Beljanski’s invention was recognized and patented.(4)
Toxicity studies were conducted, confirming the safety of the Rauwolfia vomitoria extract. Mirko Beljanski’s extract has been safely sold in the USA since 1997 under the name Rovol V®.
Since Mirko Beljanski’s death, with the support of The Beljanski Foundation, Inc., several publications by renowned academic institutions have confirmed the efficacy of Beljanski’s Rauwolfia vomitoria extract (as prepared by Dr. Beljanski and provided by Natural Source International, Ltd.) on differents lines of cancers cells and on synergy with chemotherapy.
To learn more about the plant check out Rauwolfia vomitoria Monograph
Several publications published on the anticancer effect of his Rauwolfia vomitoria extract, which he called BG-8, are dedicated to the efficiency and selectivity of its action :
Three Alkaloids as Selective Destroyers of Cancer Cells in Mice. Synergy with Classic Anticancer Drugs. Authors : M. BELJANSKI, M.S. BELJANSKI. Oncology, 43, 1986, pp. 198-203. Document not available online
Also, some publications are mentioning both Rauwolfia Vomitoria extract and Pao Pereira extract :
Agonist and/or antagonists effects of plant hormones and an anticancer alkaloid on plant DNA structure and activity. Authors : L. LE GOFF, M. BELJANSKI. IRCS Medical Science, 10, 1982, pp. 689-690. Available in English only
A New Approach to Cancer Therapy. Authors : M. BELJANSKI. Proceedings of the international seminar: Traditional Medicine: a Challenge of the 21st Century, 7-9 Nov. 1992, Calcutta (ed. in chief Biswapati Mukherjee). Available in English only
The selective anticancer agents PB-100 and BG-8 are active against human melanoma cells, but do not affect non malignant fibroblasts. Authors : S. CROCHET, M. BELJANSKI. International Journal of Oncology 8:1143-1148, 1996. Available in English only
- Traditional use of Rauwolfia vomitoria
The generic name Rauwolfia, commemorates a 16th century German physician, Leonhart Rauvolf, who travelled widely to collect medicinal plants. The specific designation vomitoria refers to the purgative and emetic properties of the bark.
Rauwolfia vomitoria belongs to the family apocynacea. It is a shrub or small tree up to 26 feet (8 m). The parts that are commonly used for herbal remedies are roots, root bark, leaves and stem-bark. Roots may be harvested non-destructively annually by cutting them 4 inches (10 cm) from the taproot, allowing for fair-trade commercialization of this traditional remedy.
Modern science has studied the phytochemical constituents of Rauwolfia since the middle of the 20th century. The main alkaloid present is called reserpine and was first discovered by Swiss scientists, Schiller and Muller of CIB Pharmaceuticals in Switzerland in 1952. Reserpine is commonly used as a marker to identify Rauwolfia.
Reserpine, according to Okpako (1991), is a major constituent of antihypertensive drugs. Taken orally, Reserpine tablets treat the symptoms of high blood pressure (1) and psychotic illnesses such as schizophrenia. Reserpine lowers blood pressure by lowering certain chemicals in the blood stream, relaxing and widening the blood vessels. Potentially serious side effects of this medication include uncontrollable movement of the legs, arms, or hands, an irregular heartbeat, or heart failure .(2) Symptoms of heart failure include a sudden weight gain of at least five pounds (2.3 kilograms), chest pain, or swelling in the legs and ankles.
You can now find the note of Dr. Marcowith’s protocols on our website.
(1) Bader, F. (1952) “Isolation of alstonine from African species of Rauwolfia”. Helvetica Chim Acta: 271-276
(2) M. BELJANSKI: “Oncotest: dépistage des potentiels cancérogènes et spécifiquement anti-cancéreux. Conceptions et perspectives nouvelles en cancérologie“. Environnement et nouvelle médecine. n°2, 1982, pp. 18-23.
(3) M. BELJANSKI, S. CROCHET “The selective anticancer agents PB-100 and BG-8 are active against human melanoma cells, but do not affect non malignant fibroblasts”. International Journal of Oncology 8:1143-1148, 1996.
(4) “Cytodiagnostic method using alstonine as a selective marker, and diagnostic kit containing marker”, patent US 5567593 A