Traditional Use of Pao Pereira

Pao pereira (Geissospermum vellosii, or Geissospermum leave velloso), also spelled Pau pereira, is a well-known tree, native to South America. This plant, which has been used in traditional medicine for centuries, is also very much a part of South American popular culture.

Use of this plant extract spans a period of over three centuries, and information about its traditional use in South America, North America and Europe has been featured in a number of important publications.

Pao Pereira traditional use

Monographie of 1848
©The Beljanski Foundation, Inc.


On December 7, 1848, Ezequiel Correa Dos Santos presented his thesis “Monographia do Geissospermum vellosii vulgo Pao pereira” at the Faculty of Medicine of Rio de Janeiro. This document has come to be regarded as the first official monograph on the benefits of Pao pereira. In the third part of the study (p.17 “Therapeutica”), Dos Santos presented twenty-one cases of therapeutic use of Pao pereira. Before outlining the details of each case history, Dr. Dos Santos summarized his study with the following statement: “The administration of the Pao pereira bark was beneficial in cases of induration of cellular tissues, chronic diarrhea, passive hemorrhage, asthenia, as well as erysipelas.”

The subject was revisited in 1879 by the journal Medical Times (Vol. X p. 276 – Philadelphia) which published a two-page article devoted to Pao pereira. After a description of the method of extracting the alkaloid pereirina, Dr. Torres Homem, Professor of Clinical Medicine at the Academy of Rio de Janeiro states, “There is not a doctor in Brazil who has not obtained good results from the use of this bark in the treatment of intermittent fevers.” He mentions in particular the case of a patient for whom quinine was ineffective but who was cured after daily baths and oral administration of the Pao pereira bark extract.

Pao pereira botanic

Pao pereira
©The Beljanski Foundation, Inc.

The article “Antimalarial remedies in French Guiana: A knowledge attitudes and practices study” published in the Journal of Ethnopharmacology [98 (2005) 351-360], details a study on 117 people from five different ethnic groups and backgrounds, taking the alcoholic extract of Geissospermum (Pao pereira) at the onset of fevers.

For example it was quite a surprise to see that one of the most renowned antimalarial Amazonian species, Geissospermum spp., was so poorly employed as curative, but on the contrary, used much more in favor as preventive.” (p. 358.) According to a questionnaire submitted by the authors, the main reason for using this traditional medicine was to “stay healthy.” (p. 355)

In line with the decline in the number of cases of malaria, Geissospermum continues to be considered very useful, though for a different purpose.

Pao pereira bark

Pao pereira bark, used for extracts, is naturally renewable

A Brazilian journal on medicinal plants, “Revista Da Flora Medicinal, (No. 9, September 1942, Rio de Janeiro), offers a botanical illustration (p. 463) and description of the tree (p. 464-465). It says that the “precious bark” can be found on “one of the most common and wellknown trees in Brazil” and “is available for all herbalists” and concludes that, “the inner bark of Pao pereira is considered as one of the best tonic and febrifuge of the Brazilian flora.”

In “Livro verde das plantas medicinais e industriais do Brasil” (1965), the therapeutic usage of the Pao pereira is described as follows: “It is an excellent tonic and powerful remedy against intermittent fevers.” It is also recommended for digestive problems, lack of appetite and constipation.

It is most likely that the Pao pereira extract made its way to Northern America and Europe around the time of the big universal exhibitions, at the end of the 19th century.
Pao pereira was exhibited at the Universal Exhibition in Philadelphia and was included in the brochure: The Empire of Brazil at the Universal Exhibition of 1876 in Philadelphia—Medicinal Plants (p. 61).

It is interesting to note that the distinction between Geissospermum vellosii, and a somewhat similar botanical called Aspidosperma, was already made in 1876. In 1895, The American Journal of Pharmacy recommended Pao pereira as an anti-fever tonic, especially to combat the periodic fevers. In 1907, The Merck Index indicates that the roots of Geissospermum vellosii have anti-peristaltic and anti-fever effects.


Pao pereira voucher
©The Beljanski Foundation, Inc.

Europe also showed early interest for Pao pereira. In “Notes, Queries and Replies” (p. 443 of “The Medical Times” London) published in 1884, Richard G. Daunt comments: “the efficacy of pereirina is extraordinary, and I have often observed its success after the failure of quinine.”

The same year in France, Dr. Tibiriça indicates in “La revue des journaux” (l’Union Médicale p.429 – Paris), “The Pereirine (extract from the bark of Pao pereira, Geissospermum leaf) fulfills the indication in a more satisfactory way than the quinine. It doubles the therapeutic action at the same time as it prevents the bad effects when pushed to a higher dose.

Belgium made Pao pereira an official “new remedy”: in 1887 in “le Journal de Médecine, de Chirurgie et de Phamacologie” (Bruxelles) published in “Nouveaux remèdes” the following note: “the alkaloid pereirine would be more effective than quinine against malarial fevers. The dose of 2 g of hydrochloride is to be taken four hours prior the access.

In 1933, in Milan, Italy, Pao pereira is listed in the dictionary of drugs “Medicamenta, Guida Teorico-pratica per Sanitari” (Dizionario dei Medicamenti p. 2389) included in the description are instructions for the pharmaceutical preparation and dosage: Internal, Decoction (30 gr: 1000) 1-2 glasses a day. Pereirine Chloride 2gr.
European scientists soon became interested in analyzing this valuable product with the means of modern chemistry.
In Belgium in 1959, Puisieux published and article on the nature of some of the alkaloids from Geissospermum (Ann Pharm Fr 1959 Oct-Dec; 17:626-33).

Everyone with a Brain Can Make a Difference !

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As part of Brain Awareness Week, please help the Beljanski Foundation explore the efficacy of the natural non-toxic plant-based extract — Pao Pereira — against brain cancer (Glioblastoma) and support our online fundraiser March 20th.

The Foundation has embarked on a new initiative to test one of Dr. Mirko Beljanski’s much researched natural cancer-fighting extracts against Glioblastoma, which is a significant challenge because it is the most common and aggressive brain tumor and it is very difficult to treat.

Despite improved technology for earlier diagnosis, no significant progress has been made with this cancer. This new effort is stimulated by Dr. Beljanski’s earlier research conducted at the Pasteur Institute showing that extracts of Pao pereira have a broad-spectrum anti-cancer activity and that the active agents in these extracts cross the blood brain barrier. Dr. Beljanski’s research on Glioblastoma has been published and is available on the Beljanski Foundation website under numbers:123124125128, and 131.

Want to know more? 
Years of fundamental research in oncology have shown that most cancers have a common denominator — destabilized DNA. Molecular biologist, Mirko Beljanski, PhD, was a forerunner of this finding and his discoveries of natural plant extracts that act selectively on destabilized DNA have been validated through the research program at the Beljanski Foundation.

Results of the highly successful research of Beljanski’s plant extracts on ovarian and pancreatic cancer at Kansas University and on prostate cancer at Columbia University have been published in scientific journals.

Donate to Support Brain Cancer Research!

Cancer’s cause, Cancer’s Cure: The Hard Truth Book Review

The Hard Truth Book reviewCancer remains the second most common cause of death in the US, accounting for nearly 1 of every 4 deaths. Over half a million cancer death are forecast in 2014 alone.
And we can’t do a damn thing about it.
Or can we?
Is there help anywhere?
Yes, there is. The answer has been found and suppressed, yet is available to you, dear reader. Read on.

Dr Morton Walker, DPM has written a seminal book, Cancer’s Cause, Cancer’s cure, about Mirko Beljanski, PhD who discovered the cause and cure for our most enduring nightmare.

This is a review of that book

Read the entire article of the book review by LD Sledge and published on The Hard Truth magazine

Morton Walker book’s in Serbian

Morton Walker - Serbian version

Not only was the 7th European Congress of Integrative Medicine (ECIM) dedicated to the memory of Mirko Beljanski, but a documentary movie on his life and major scientific achievements was presented at the opening session.

In addition, copies of Morton Walker’s book “Cancer’s Cause, Cancer’s Cure” that had been translated into Serbian (Uzrok raka, lek za rak) were distributed to all Congress participants (the book was also available in English).

New article on Alternative to castration therapy

Health Science Institute (HSI) produced an article dedicated to the last scientific study conducted at Nanjing University about the effectiveness of Pao pereira extract, even on advanced prostate cancers that are no longer responsive to hormone therapy.

It is well known that cancer cells can become resistant to anti-hormone treatment, leaving many patients with few therapeutic options, and this latest paper could give hope to many.

Read this article written by Michelle Cagan : Why choose castration therapy? Rainforest plant beats even late-stage, aggressive prostate cancer.

Dr. Ralph Moss

Capture d’écran 2015-09-18 à 09.27.46Dr Ralph Moss has dedicated a column in the current issue of his “Cancer Decisions” newsletter to Mirko Beljanski, PhD, and to the achievements of The Beljanski Foundation while carrying on Dr Beljanski’s legacy.

Setting aside all controversy, Dr. Moss reports on the many recent scientific and clinical studies published by several prestigious universities on prostate, ovarian and pancreatic cancers, all of which validate Dr Beljanski’s work and its natural and selective approach.

If you wish to read the article, check Dr. Ralph Moss website :


New Article About Mirko Beljanski in Spain

Once again, Pr. Mirko Beljanski’s work has been acknowledged overseas ! Today, it’s in Spain in “La Revista de Medicinas Complementarias. Medicina Holística”.

This time, “La Revista de Medicinas Complementarias. Medicina Holística, edited by the AMC (The Spanish Asociación de Medicinas Complementarias), has published one new article (n 84) on Dr. Beljanski’s research.

The very first sentences reveals the excitement of the Spanish scientific community. « Hoy la consagración póstuma de Mirko Beljanski nos llega de los EE.UU, donde los descubrimientos des investigador han llamado la atención. El trabajo de Mirko Beljanski no sólo queda confirmado sino también ampliado ».
Here is the translation for non-Spanish speakers like myself:
“Today’s posthumous consecration of Mirko Beljanski comes from the U.S., where discoveries have caught the interest of researchers. Dr. Mirko Beljanski’s work is not only confirmed but also extended.”


Article on the Effects of Pao Pereira on Ovarian and Pancreatic cancers

Breakthrough studies reveal miracle plant defeats the two incurable cancers

Michele Cagan wrote an article about the last research published by Kansas University Medical Center on the effects of Pao Pereira on pancreatic and Ovarian cancers, it was published on december 2013 (Vol 18 N 4) on the magazine Health Sciences Institute.

That article is titled : Breakthrough studies reveal miracle plant defeats the two incurable cancers – pancreatic and ovarian

To read the article:  Breakthrough studies reveal miracle plant defeats the two incurable cancers – pancreatic and ovarian (HSI – Vol 18 N 4)

Article on by Dale O’Brien, MD

Dr. Dale O’Brien (Dale O’Brien, MD, MPH is the Executive Director of Cancer Patients Alliance and the Medical Director of its Pancreatica and CancerPACT projects). Dr. Dale O’Brien has been an affiliate of the European Branch headquarters of the World Health Organization (in Copenhagen, Denmark) and the Epidemic Intelligence Service of the Centers for Disease Control and Prevention (CDC). He currently serves as an Assistant Clinical Professor at the University of California at Davis in the Department of Medicine.

Dr O’ Brien dedicated a blog entry to our Pao pereira /pancreas paper: “Pre-clinical study of Natural Product from Amazon tree: Geissospermum vellosii


Cancer’s Cause Cancer’s Cure by Morton Walker


Last November 2013, Patricia Ross was the guest of the Extreme Health Radio

The journalists Kate and Justin had a very fascinating interview with Dr. Patricia Ross. It had originally been scheduled to speak with Dr. Morton Walker about his book called Cancer’s Cause, Cancer’s Cure but that didn’t work out so Dr. Ross was gracious enough to step in and talk about this amazing book by Dr. Walker.

In fact Dr. Ross knows more about this book than anyone other than Morton Walker himself because she edited and did the rewriting herself. She’s a master at turning technical data into bite sized absorbable information that’s easy to digest.

Click here to listen to listen the interview: