41 – ARN-messager: intermédiaire direct dans la synthèse des liaisons peptidiques

Colloques Internationaux du C.N.R.S., Marseille, 1963, pp. 39-44. (Mécanismes de régulation des activités cellulaires chez les micro-organismes). Available in French only ABSTRACT: English summary : The formation of peptides in the presence of ribonucleoside-5′-triphosphates and of polypeptide synthetases from Alcaligenes faecalis requires the participation on an RNA fraction. Active RNA obtained from these bacteria has been identified by several procedures as being messenger RNA and has been partially purified by ammonium-sulfate fractionation. This RNA fraction has the ability to fix un-competitively L-amino-acids, forming a “RNA-AA” complex which, when isolated and incubated again in Tris buffer without the addition from various origins, acts as an amino-acids acceptor in the presence of Alcaligenes faecalis enzymes.Read the full publication