Precancerous condition

Goal: Prevent the development of a tumor in individuals who are precancerous, with a high likelihood of developing a cancer without being diagnosed.

Characteristics of a precancerous condition:

Risk of cancer increases with age.  Other risk factors: presence of inflammatory condition such as benign prostatic hyperplasia which may progress to a tumor;  immediate family history of cancer;  presence of urinary disorders,  obesity, sedentary lifestyle, poor diet.

The Beljanski approach begins with a regimen to address obesity, along with a two month course of Pao pereira and Rauwolfia vomitoria extracts at appropriate dosage.

These extracts contain alkaloids of the beta-carboline class; alstonine (from Rauwolfia vomitoria, native to Africa) and flavopereirine (from Pao pereira, a tree that grows in South America) that react to the open sites of cancerous DNA and prevent genome duplication. Those extracts are known to induce death of precancerous cells and reduce inflammation, using different pathways (1,2,3).  

Also useful at this precancerous stage is the consumption of the green tea blend identified by Beljanski.  Recent studies have shown that this blend exerts a significant anti-cancer effect and the well- known anti-oxidant effects of green tea can help protect DNA from damage (4).

Localized cancerous condition (Stages 1 and 2)

Goal: Synergy of Beljanski approach with radiotherapy and chemotherapy, reduction of side effects and preservation of immunity.

Beljanski approach is used to complement Beljanski treatment consisting of taking extracts such as Pao pereira and Rauwolfia vomitoria, in suitable doses (5,6). They will work in synergy with other therapies to destroy cancer cells (7,8,9,10).

In addition, taking Beljanski’s Ginkgo biloba extract in conjunction with radiotherapy or brachytherapy will reduce the side effects of these treatments (11).  Ginkgo biloba is a tree that survived the destructive nuclear radiation in Japan.  The yellow leaf Ginkgo extract can protect tissues from radiation induced damage.  This extract helps reduce the side effects of radiotherapy (and brachytherapy), and prevent fibrosis caused by radiation.

Finally, in the event of a risk of low white blood cells or platelets counts due to chemotherapy, a sublingual intake of Beljanski’s RNA fragments, the day before each round of treatment enables the return of immunity, the regeneration of platelets and neutrophils, activation of Natural Killer cells and prevention of chromosomal breaks (12,13).  Beljanski’s RNA fragments are made from  a safe strain of E. coli K12 bacteria.  They facilitate proliferation of healthy white blood cells and platelets, replenishing the immune system.

Beljanski’s green tea blend  has broad spectrum anti-cancer activity and is recommended not only for cancer prevention but as part of the Beljanski approach to cancer treatment for potential suppression of tumor growth.

Advanced cancerous state (Stages 3 and 4)

Goal: Effectiveness of Beljanski extracts when chemotherapy is no longer effective.

The cancer is no longer localized, it has spread to surrounding and even distant organs including lungs, liver, lymph nodes and entered an advanced stage. Chemotherapy or hormone therapy treatments will be introduced into the bloodstream to reach the metastases.

At this stage, Beljanski treatment includes Pao pereira and Rauwolfia vomitoria extracts to attack cancer cells weakened by conventional treatments.  The active compounds in the extracts circulate in the blood,  and in the case of Pao pereira will even reach metastases in the brain (passing the meningeal barrier). The anti-cancer activity of the extracts are all the more effective when combined with conventional treatments—synergy of action. Yellow leaf Ginkgo biloba extract for its regulatory effect on globulins and enzymatic proteins, its protection of the genome and its reduction of the side effects of radiation therapies, brings comfort to patients in aggressive treatments.

For treatments seriously affecting the hematopoietic cells, and the essential immunity of the patient, taking RNA fragments before and during treatments will protect and restore immunity (platelets and white blood cells) without inducing proliferation of malignant cells. These sublingual doses should be taken before and during chemotherapy to avoid aplasia.

In some cases, after extended therapies, the tumor has metastasized,  has developed resistance to chemotherapy and continues to grow. Conventional therapies then have no solution to provide.  At this stage, Beljanski extracts still have the major advantage of being effective against hormone-resistant and chemo-resistant tumors (14,15,16).

Beljanski’s green tea is also important for patients with advanced cancers as part of a healthy lifestyle in which the consumption of food and beverage with anti-cancer effects provides support for the anti-cancer regimen.

References

  1. Liu J, Fang T, Li M, Song Y, Li J, Xue Z , Li J, Bu D, Liu W, Zeng Q, Zhang Y, Yun S, Huang R, Yan J. Pao Pereira extract attenuates testosterone-induced benign prostatic hyperplasia in rats by inhibiting 5α-reductase. Scientific Reports (2019) 9:19703. https://www.nature.com/articles/s41598-019-56145-z
  2. Dong Y,  Liu J, Xue Z, Sun J, Huang Z, Jing Y, Han B, Shen B, Yan J and Huang R.  Pao Pereira extract suppresses benign prostatic hyperplasia by inhibiting inflammation-associated NFκB signaling.  BMC Complementary Medicine and Therapies volume 20, Article number: 150 (2020). https://www.researchgate.net/publication/341439152
  3. Fang, T.,  Xue, Z., Li, J.,  Liu, J., Wu, D., Li, M., Song, Y.,  Yun, S. and Yan, J. Rauwolfia vomitoria extract suppresses benign prostatic hyperplasia by reducing androgen receptor and 5α-reductase expression in a rat model. Journal of Integrative Medicine. 2020 Dec 3: S2095-4964(20)30134-5. https://pubmed.ncbi.nlm.nih.gov/33341427/
  4. Ping Chen and Qi Chen, Effects of Different Tea Products on the Growth of Cancer Cells. EC Nutrition 14.12 (2019): 01-13. www.ecronicon.com/ecnu/pdf/ECNU-14-00734.pdf
  5. Bemis,  D., Capodice, J., Gorroochurn, P., Katz, A. and Buttyan. Anti-prostate cancer activity of a ß-carboline alkaloid enriched extract from Rauwolfia vomitoria. International Journal of Oncology. 29: 1065-1073, 2006. https://pubmed.ncbi.nlm.nih.gov/17016636/
  6. Bemis,  D., Capodice, J., Desai, M., Gorroochurn, P., Katz, A. and Buttyan. Beta-Carboline Alkaloid–Enriched Extract from the Amazonian Rain Forest Tree Pao Pereira Suppresses Prostate Cancer Cells. Journal of the Society for Integrative Oncology, Vol 7, No 2 (Spring), 2009: pp 59–65 https://www.researchgate.net/publication/26248012
  7. Yu, J. and Chen, Q. Department of Pharmacology, Toxicology & Therapeutics, University of Kansas Medical Center.  “The Plant Extract of Pao Pereira Potentiates Carboplatin Effects Against Ovarian Cancer” Pharmaceutical Biology 2014 Jan; 52(1):36-43. https://www.researchgate.net/publication/256608022
  8. Yu, J, Ma, Y., Drisko, J., and Chen, Q. Department of Pharmacology, Toxicology & Therapeutics, University of Kansas Medical Center.  “Antitumor Activities of Rauwolfia Vomitoria Extract and Potentiation of Carboplatin Effects Against Ovarian Cancer” Current Therapeutic Research, 75(2013)8-14. https://www.researchgate.net/publication/256691747
  9. Yu, J., Chen, Q., and Drisko, J. Department of Pharmacology, Toxicology & Therapeutics, University of Kansas Medical Center. “Inhibition of Pancreatic Cancer and Potentiation of Gemcitabine Effects by the Extract of Pao Pereira” Oncology Reports 2013 Jul; 30(1):149-56. https://www.researchgate.net/publication/236837135
  10. Yu, J. and Chen, Q. Department of Pharmacology, Toxicology & Therapeutics, University of Kansas Medical Center. “Antitumor Activities of Rauwolfia Vomitoria and Potentiation of Gemcitabine Effects Against Pancreatic Cancer” Integr Cancer Ther 2014; 13:217-225. https://www.researchgate.net/publication/261882862
  11. Beljanski M, Cuasse JE, Nawrocki T, Beljanski M.  “Human Skin Fibrosis RNase Search for a Biological Inhibitor-Regulator“. Deutsche Zeitschrift für Onkologie, 26, 5, 1994, pp. 137-139. https://www.beljanski.org/beljanski-scientific-publications/127-human-skin-fibrosis-rnase-search-for-a-biological-inhibitor-regulator/
  12. Beljanski M, Plawecki M. Particular RNA fragments as promoters of leukocyte and platelet formation in rabbits.  Exp Cell Biol 1979;47(3):218-25. https://www.beljanski.org/beljanski-scientific-publications/83-particular-rna-fragments-as-promoters-of-leukocyte-and-platelet-formations-in-rabbits/
  13. Levin RD, Daehler M, Grutsch JF, Hall JL, Gupta D, Lis CG.   Dose escalation study of an anti-thrombocytopenic agent in patients with chemotherapy induced thrombocytopenia.  BMC Cancer. 2010 Oct 19;10:565. https://pubmed.ncbi.nlm.nih.gov/20955619/
  14. Chang C., Zhao W., Xie B., Deng Y., Han T., Cui Y., Dai Y., Zhang Z., Gao J., Guo H., Yan J. Pao pereira extract suppresses castration resistant prostate cancer cell growth, survival and invasion through inhibition of NFκB signaling. Integr. Cancer Ther. 2013 first published on November 27, 2013 as https://journals.sagepub.com/doi/full/10.1177/1534735413510557
  15. Dong, R., Chen, P., and Chen, Q. Extract of the medicinal plant Pao Pereira inhibits pancreatic cancer stem-like cells in vitro and in vivo. Integrative Cancer Therapies 2018 Dec;17(4):1204-1215 https://www.researchgate.net/publication/326286377
  16. Dong, R., Chen, P. and Chen, Q. Inhibition of pancreatic cancer stem cells by Rauwolfia vomitoria extract. Oncology Reports. Oncology Reports 2018 Dec;40(6):3144-3154. https://www.researchgate.net/publication/327731579