101 – Growth inhibition of crown-gall tissues in relation to the struture and activity of DNA

Authors : L. LE GOFF, J. ROUSSAUX, Y. AARON-DA-CUNHA, M. BELJANSKI
Physiol. Plant., 64, 1985, pp. 177-184.

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ABSTRACT: The growth of Crown-gall cells cultures in vitro (Nicotiana tabacum L. cv. White Burley and Parthenocissus tricuspidata cv. Veitchii) is inhibited by alstonine (BG-8), a plant alkaloid, the anti-cancer effect of which has previously been demonstrated on animals and plants. The growth of normal cells is only slightly affected. The inhibitory effect of BG-8 on crown-gall cells is antagonized byindole-3-ecatic acid (IAA) added to the culture medium. Kinetin associated with IAA does not prevent this inhibitory effect. BG-8 present in the culture medium containing the two types of hormones seems to modify the later hormonal requirement of Parthenocissus crown-gall tissues…

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